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Validation of an HPLC-CAD Method for Determination of Lipid Content in LNP-Encapsulated COVID-19 mRNA Vaccines

Lipid nanoparticles (LNPs) are widely used as delivery systems for mRNA vaccines. The stability and bilayer fluidity of LNPs are determined by the properties and contents of the various lipids used in the formulation system, and the delivery efficiency of LNPs largely depends on the lipid compositio...

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Detalles Bibliográficos
Autores principales: Yu, Xiaojuan, Yu, Chuanfei, Wu, Xiaohong, Cui, Yu, Liu, Xiaoda, Jin, Yan, Li, Yuhua, Wang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222414/
https://www.ncbi.nlm.nih.gov/pubmed/37243041
http://dx.doi.org/10.3390/vaccines11050937