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Validation of an HPLC-CAD Method for Determination of Lipid Content in LNP-Encapsulated COVID-19 mRNA Vaccines
Lipid nanoparticles (LNPs) are widely used as delivery systems for mRNA vaccines. The stability and bilayer fluidity of LNPs are determined by the properties and contents of the various lipids used in the formulation system, and the delivery efficiency of LNPs largely depends on the lipid compositio...
Autores principales: | Yu, Xiaojuan, Yu, Chuanfei, Wu, Xiaohong, Cui, Yu, Liu, Xiaoda, Jin, Yan, Li, Yuhua, Wang, Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222414/ https://www.ncbi.nlm.nih.gov/pubmed/37243041 http://dx.doi.org/10.3390/vaccines11050937 |
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