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MKX-AS1 Gene Expression Associated with Variation in Drug Response to Oxaliplatin and Clinical Outcomes in Colorectal Cancer Patients

Oxaliplatin (OXAL) is a commonly used chemotherapy for treating colorectal cancer (CRC). A recent genome wide association study (GWAS) showed that a genetic variant (rs11006706) in the lncRNA gene MKX-AS1 and partnered sense gene MKX could impact the response of genetically varied cell lines to OXAL...

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Detalles Bibliográficos
Autores principales: Gonzalez, Ricardo D., Small, George W., Green, Adrian J., Akhtari, Farida S., Motsinger-Reif, Alison A., Quintanilha, Julia C. F., Havener, Tammy M., Reif, David M., McLeod, Howard L., Wiltshire, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222429/
https://www.ncbi.nlm.nih.gov/pubmed/37242540
http://dx.doi.org/10.3390/ph16050757