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Chronic Periodontal Infection and Not Iatrogenic Interference Is the Trigger of Medication-Related Osteonecrosis of the Jaw: Insights from a Large Animal Study (PerioBRONJ Pig Model)

Background and Objectives: Antiresorptive drugs are widely used in osteology and oncology. An important adverse effect of these drugs is medication-induced osteonecrosis of the jaw (MRONJ). There is scientific uncertainty about the underlying pathomechanism of MRONJ. A promising theory suspects infe...

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Detalles Bibliográficos
Autores principales: Troeltzsch, Matthias, Zeiter, Stephan, Arens, Daniel, Nehrbass, Dirk, Probst, Florian A., Liokatis, Paris, Ehrenfeld, Michael, Otto, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222433/
https://www.ncbi.nlm.nih.gov/pubmed/37241232
http://dx.doi.org/10.3390/medicina59051000