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Nonselective and A2a-Selective Inhibition of Adenosine Receptors Modulates Renal Perfusion and Excretion Depending on the Duration of Streptozotocin-Induced Diabetes in Rats

Long-lasting hyperglycaemia may alter the role of adenosine-dependent receptors (P1R) in the control of kidney function. We investigated how P1R activity affects renal circulation and excretion in diabetic (DM) and normoglycaemic (NG) rats; the receptors’ interactions with bioavailable NO and H(2)O(...

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Detalles Bibliográficos
Autores principales: Sitek, Joanna Dorota, Kuczeriszka, Marta, Walkowska, Agnieszka, Kompanowska-Jezierska, Elżbieta, Dobrowolski, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222446/
https://www.ncbi.nlm.nih.gov/pubmed/37242515
http://dx.doi.org/10.3390/ph16050732