Iminosugar-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors as Potential Anti-Pancreatic Cancer Agents

The nicotinamide phosphoribosyltransferase (NAMPT) is considered a very promising therapeutic target because it is overexpressed in pancreatic cancer. Although many inhibitors have been prepared and tested, clinical trials have shown that NAMPT inhibition may result in severe haematological toxicity...

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Detalles Bibliográficos
Autores principales: Conforti, Irene, Benzi, Andrea, Caffa, Irene, Bruzzone, Santina, Nencioni, Alessio, Marra, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222582/
https://www.ncbi.nlm.nih.gov/pubmed/37242714
http://dx.doi.org/10.3390/pharmaceutics15051472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222582/
https://www.ncbi.nlm.nih.gov/pubmed/37242714
http://dx.doi.org/10.3390/pharmaceutics15051472

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