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Metastatic Colorectal Cancer Patient with Microsatellite Stability and Germline BRAC2 Mutation Shows a Complete Response to Olaparib in Combination with a PD-1 Inhibitor and Bevacizumab: A Case Report and Review of the Literature

Metastatic colorectal cancer (mCRC) has a poor prognosis. Combining chemotherapy with targeted therapy constitutes a basic form of mCRC treatment. Immune checkpoint inhibitors have been recommended for microsatellite instability mCRC, while most patients harboring microsatellite stability (MSS) or p...

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Detalles Bibliográficos
Autores principales: Song, Minghan, Zeng, Xianrong, Wu, Qian, Huang, Jie, Dong, Jiayi, Shao, Lijuan, Sun, Zihao, Lin, Yiguang, Chen, Size
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222588/
https://www.ncbi.nlm.nih.gov/pubmed/37240828
http://dx.doi.org/10.3390/life13051183