A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice

Equine-derived antitoxin (BAT(®)) is the only treatment for botulism from botulinum neurotoxin serotype G (BoNT/G). BAT(®) is a foreign protein with potentially severe adverse effects and is not renewable. To develop a safe, more potent, and renewable antitoxin, humanized monoclonal antibodies (mAbs...

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Detalles Bibliográficos
Autores principales: Fan, Yongfeng, Lou, Jianlong, Tam, Christina C., Wen, Weihua, Conrad, Fraser, Leal da Silva Alves, Priscila, Cheng, Luisa W., Garcia-Rodriguez, Consuelo, Farr-Jones, Shauna, Marks, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222606/
https://www.ncbi.nlm.nih.gov/pubmed/37235351
http://dx.doi.org/10.3390/toxins15050316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222606/
https://www.ncbi.nlm.nih.gov/pubmed/37235351
http://dx.doi.org/10.3390/toxins15050316

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