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A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice
Equine-derived antitoxin (BAT(®)) is the only treatment for botulism from botulinum neurotoxin serotype G (BoNT/G). BAT(®) is a foreign protein with potentially severe adverse effects and is not renewable. To develop a safe, more potent, and renewable antitoxin, humanized monoclonal antibodies (mAbs...
Autores principales: | Fan, Yongfeng, Lou, Jianlong, Tam, Christina C., Wen, Weihua, Conrad, Fraser, Leal da Silva Alves, Priscila, Cheng, Luisa W., Garcia-Rodriguez, Consuelo, Farr-Jones, Shauna, Marks, James D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222606/ https://www.ncbi.nlm.nih.gov/pubmed/37235351 http://dx.doi.org/10.3390/toxins15050316 |
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