Synthesis and Molecular Docking Studies of Alkoxy- and Imidazole-Substituted Xanthones as α-Amylase and α-Glucosidase Inhibitors

Current antidiabetic drugs have severe side effects, which may be minimized by new selective molecules that strongly inhibit α-glucosidase and weakly inhibit α-amylase. We have synthesized novel alkoxy-substituted xanthones and imidazole-substituted xanthones and have evaluated them for their in sil...

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Detalles Bibliográficos
Autores principales: Aguila-Muñoz, Dolores G., Vázquez-Lira, Gabriel, Sarmiento-Tlale, Erika, Cruz-López, María C., Jiménez-Montejo, Fabiola E., López y López, Víctor E., Escalante, Carlos H., Andrade-Pavón, Dulce, Gómez-García, Omar, Tamariz, Joaquín, Mendieta-Moctezuma, Aarón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222686/
https://www.ncbi.nlm.nih.gov/pubmed/37241920
http://dx.doi.org/10.3390/molecules28104180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222686/
https://www.ncbi.nlm.nih.gov/pubmed/37241920
http://dx.doi.org/10.3390/molecules28104180

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