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The Inherited Intestinal Microbiota from Myeloid-Specific ZIP8KO Mice Impairs Pulmonary Host Defense against Pneumococcal Pneumonia

Intestinal dysbiosis increases susceptibility to infection through the alteration of metabolic profiles, which increases morbidity. Zinc (Zn) homeostasis in mammals is tightly regulated by 24 Zn transporters. ZIP8 is unique in that it is required by myeloid cells to maintain proper host defense agai...

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Detalles Bibliográficos
Autores principales: Samuelson, Derrick R., Smith, Deandra R., Cunningham, Kelly C., Haq, Sabah, Villageliú, Daniel N., Ellis, Christi M., Chowdhury, Niaz Bahar, Ramer-Tait, Amanda E., Price, Jeffrey D., Knoell, Daren L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222741/
https://www.ncbi.nlm.nih.gov/pubmed/37242309
http://dx.doi.org/10.3390/pathogens12050639