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The Inherited Intestinal Microbiota from Myeloid-Specific ZIP8KO Mice Impairs Pulmonary Host Defense against Pneumococcal Pneumonia
Intestinal dysbiosis increases susceptibility to infection through the alteration of metabolic profiles, which increases morbidity. Zinc (Zn) homeostasis in mammals is tightly regulated by 24 Zn transporters. ZIP8 is unique in that it is required by myeloid cells to maintain proper host defense agai...
Autores principales: | Samuelson, Derrick R., Smith, Deandra R., Cunningham, Kelly C., Haq, Sabah, Villageliú, Daniel N., Ellis, Christi M., Chowdhury, Niaz Bahar, Ramer-Tait, Amanda E., Price, Jeffrey D., Knoell, Daren L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222741/ https://www.ncbi.nlm.nih.gov/pubmed/37242309 http://dx.doi.org/10.3390/pathogens12050639 |
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