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Challenges in HIV-1 Latent Reservoir and Target Cell Quantification in CAR-T Cell and Other Lentiviral Gene Modifying HIV Cure Strategies

Gene-modification therapies are at the forefront of HIV-1 cure strategies. Chimeric antigen receptor (CAR)-T cells pose a potential approach to target infected cells during antiretroviral therapy or following analytical treatment interruption (ATI). However, there are technical challenges in the qua...

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Detalles Bibliográficos
Autores principales: Buck, Amanda M., Deveau, Tyler-Marie, Henrich, Timothy J., Deitchman, Amelia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222761/
https://www.ncbi.nlm.nih.gov/pubmed/37243212
http://dx.doi.org/10.3390/v15051126