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Hydrophobic Modification of Poly(γ-glutamic acid) by Grafting 4-Phenyl-butyl Side Groups for the Encapsulation and Release of Doxorubicin

The delivery of drugs is a great challenge, since most of active pharmaceutical ingredients developed today are hydrophobic and poorly water soluble. From this perspective, drug encapsulation on biodegradable and biocompatible polymers can surpass this problem. Poly(γ-glutamic acid) (PGGA), a bioedi...

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Detalles Bibliográficos
Autores principales: Dorost, Porochista, García-Alvarez, Montserrat, Martínez de Ilarduya, Antxon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222848/
https://www.ncbi.nlm.nih.gov/pubmed/37242619
http://dx.doi.org/10.3390/pharmaceutics15051377