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Ionizable Lipids with Triazole Moiety from Click Reaction for LNP-Based mRNA Delivery

Ionizable lipid-containing lipid nanoparticles (LNPs) as a non-viral vector with good safety and potency have been considered as an ideal delivery system for gene therapy. The screening of ionizable lipid libraries with common features but diverse structures holds the promise of finding new candidat...

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Detalles Bibliográficos
Autores principales: Wang, Yixiang, Si, Xiao, Feng, Yi, Feng, Dan, Xu, Xiaoyu, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223118/
https://www.ncbi.nlm.nih.gov/pubmed/37241787
http://dx.doi.org/10.3390/molecules28104046