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Ionizable Lipids with Triazole Moiety from Click Reaction for LNP-Based mRNA Delivery
Ionizable lipid-containing lipid nanoparticles (LNPs) as a non-viral vector with good safety and potency have been considered as an ideal delivery system for gene therapy. The screening of ionizable lipid libraries with common features but diverse structures holds the promise of finding new candidat...
Autores principales: | Wang, Yixiang, Si, Xiao, Feng, Yi, Feng, Dan, Xu, Xiaoyu, Zhang, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223118/ https://www.ncbi.nlm.nih.gov/pubmed/37241787 http://dx.doi.org/10.3390/molecules28104046 |
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