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Combined Live Oral Priming and Intramuscular Boosting Regimen with Rotarix(®) and a Nanoparticle-Based Trivalent Rotavirus Vaccine Evaluated in Gnotobiotic Pig Models of G4P[6] and G1P[8] Human Rotavirus Infection

Human rotavirus (HRV) is the causative agent of severe dehydrating diarrhea in children under the age of five, resulting in up to 215,000 deaths each year. These deaths almost exclusively occur in low- and middle-income countries where vaccine efficacy is the lowest due to chronic malnutrition, gut...

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Detalles Bibliográficos
Autores principales: Hensley, Casey, Nyblade, Charlotte, Zhou, Peng, Parreño, Viviana, Ramesh, Ashwin, Frazier, Annie, Frazier, Maggie, Garrison, Sarah, Fantasia-Davis, Ariana, Cai, Ruiqing, Huang, Peng-Wei, Xia, Ming, Tan, Ming, Yuan, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223133/
https://www.ncbi.nlm.nih.gov/pubmed/37243031
http://dx.doi.org/10.3390/vaccines11050927