Cargando…
Combined Live Oral Priming and Intramuscular Boosting Regimen with Rotarix(®) and a Nanoparticle-Based Trivalent Rotavirus Vaccine Evaluated in Gnotobiotic Pig Models of G4P[6] and G1P[8] Human Rotavirus Infection
Human rotavirus (HRV) is the causative agent of severe dehydrating diarrhea in children under the age of five, resulting in up to 215,000 deaths each year. These deaths almost exclusively occur in low- and middle-income countries where vaccine efficacy is the lowest due to chronic malnutrition, gut...
Autores principales: | Hensley, Casey, Nyblade, Charlotte, Zhou, Peng, Parreño, Viviana, Ramesh, Ashwin, Frazier, Annie, Frazier, Maggie, Garrison, Sarah, Fantasia-Davis, Ariana, Cai, Ruiqing, Huang, Peng-Wei, Xia, Ming, Tan, Ming, Yuan, Lijuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223133/ https://www.ncbi.nlm.nih.gov/pubmed/37243031 http://dx.doi.org/10.3390/vaccines11050927 |
Ejemplares similares
-
A New Gnotobiotic Pig Model of P[6] Human Rotavirus Infection and Disease for Preclinical Evaluation of Rotavirus Vaccines
por: Nyblade, Charlotte, et al.
Publicado: (2022) -
Human Rotavirus Replicates in Salivary Glands and Primes Immune Responses in Facial and Intestinal Lymphoid Tissues of Gnotobiotic Pigs
por: Nyblade, Charlotte, et al.
Publicado: (2023) -
Probiotic as Adjuvant Significantly Improves Protection of the Lanzhou Trivalent Rotavirus Vaccine against Heterologous Challenge in a Gnotobiotic Pig Model of Human Rotavirus Infection and Disease
por: Parreno, Viviana, et al.
Publicado: (2022) -
Establishment of a gnotobiotic pig model of Clostridioides difficile infection and disease
por: Nyblade, Charlotte, et al.
Publicado: (2022) -
Comparative analysis of the Rotarix™ vaccine strain and G1P[8] rotaviruses detected before and after vaccine introduction in Belgium
por: Zeller, Mark, et al.
Publicado: (2017)