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Synthesis of Aminoalkyl Sclareolide Derivatives and Antifungal Activity Studies

Sclareolide was developed as an efficient C-nucleophilic reagent for an asymmetric Mannich addition reaction with a series of N-tert-butylsulfinyl aldimines. The Mannich reaction was carried out under mild conditions, affording the corresponding aminoalkyl sclareolide derivatives with up to 98% yiel...

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Detalles Bibliográficos
Autores principales: Li, Ziyi, Gao, Hua, Mei, Haibo, Wu, Guangwei, Soloshonok, Vadim A., Han, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223150/
https://www.ncbi.nlm.nih.gov/pubmed/37241807
http://dx.doi.org/10.3390/molecules28104067