An Artificial Peptide-Based Bifunctional HIV-1 Entry Inhibitor That Interferes with Viral Glycoprotein-41 Six-Helix Bundle Formation and Antagonizes CCR5 on the Host Cell Membrane

Human immunodeficiency virus type 1 (HIV-1) is characterized by high variability and drug resistance. This has necessitated the development of antivirals with a new chemotype and therapy. We previously identified an artificial peptide with non-native protein sequence, AP3, with the potential to inhi...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Li, Qing, Sun, Lujia, Wang, Xinling, Wang, Huan, Zhang, Wenpeng, Li, Jiahui, Liu, Yang, Lu, Lu, Jiang, Shibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223265/
https://www.ncbi.nlm.nih.gov/pubmed/37243126
http://dx.doi.org/10.3390/v15051038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223265/
https://www.ncbi.nlm.nih.gov/pubmed/37243126
http://dx.doi.org/10.3390/v15051038

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