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PPAR-γ Agonist GW1929 Targeted to Macrophages with Dendrimer–Graphene Nanostars Reduces Liver Fibrosis and Inflammation

Macrophages play essential roles during the progression of chronic liver disease. They actively participate in the response to liver damage and in the balance between fibrogenesis and regression. The activation of the PPARγ nuclear receptor in macrophages has traditionally been associated with an an...

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Detalles Bibliográficos
Autores principales: Moreno-Lanceta, Alazne, Medrano-Bosch, Mireia, Simón-Codina, Blanca, Barber-González, Montserrat, Jiménez, Wladimiro, Melgar-Lesmes, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223394/
https://www.ncbi.nlm.nih.gov/pubmed/37242695
http://dx.doi.org/10.3390/pharmaceutics15051452