Kinetics of Water-Induced Amorphous Phase Separation in Amorphous Solid Dispersions via Raman Mapping

The poor bioavailability of an active pharmaceutical ingredient (API) can be enhanced by dissolving it in a polymeric matrix. This formulation strategy is commonly known as amorphous solid dispersion (ASD). API crystallization and/or amorphous phase separation can be detrimental to the bioavailabili...

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Detalles Bibliográficos
Autores principales: Krummnow, Adrian, Danzer, Andreas, Voges, Kristin, Kyeremateng, Samuel O., Degenhardt, Matthias, Sadowski, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223424/
https://www.ncbi.nlm.nih.gov/pubmed/37242637
http://dx.doi.org/10.3390/pharmaceutics15051395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223424/
https://www.ncbi.nlm.nih.gov/pubmed/37242637
http://dx.doi.org/10.3390/pharmaceutics15051395

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