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MPrESS: An R-Package for Accurately Predicting Power for Comparisons of 16S rRNA Microbiome Taxa Distributions including Simulation by Dirichlet Mixture Modeling

Deep sequencing has revealed that the 16S rRNA gene composition of the human microbiome can vary between populations. However, when existing data are insufficient to address the desired study questions due to limited sample sizes, Dirichlet mixture modeling (DMM) can simulate 16S rRNA gene predictio...

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Detalles Bibliográficos
Autores principales: Clarke, Thomas H., Greco, Chris, Brinkac, Lauren, Nelson, Karen E., Singh, Harinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223547/
https://www.ncbi.nlm.nih.gov/pubmed/37317139
http://dx.doi.org/10.3390/microorganisms11051166