Guanidines: Synthesis of Novel Histamine H(3)R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect

This study examines the properties of novel guanidines, designed and synthesized as histamine H(3)R antagonists/inverse agonists with additional pharmacological targets. We evaluated their potential against two targets viz., inhibition of MDA-MB-231, and MCF-7 breast cancer cells viability and inhib...

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Detalles Bibliográficos
Autores principales: Staszewski, Marek, Iwan, Magdalena, Werner, Tobias, Bajda, Marek, Godyń, Justyna, Latacz, Gniewomir, Korga-Plewko, Agnieszka, Kubik, Joanna, Szałaj, Natalia, Stark, Holger, Malawska, Barbara, Więckowska, Anna, Walczyński, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223552/
https://www.ncbi.nlm.nih.gov/pubmed/37242458
http://dx.doi.org/10.3390/ph16050675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223552/
https://www.ncbi.nlm.nih.gov/pubmed/37242458
http://dx.doi.org/10.3390/ph16050675

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