Generic Workflow to Predict Medicine Concentrations in Human Milk Using Physiologically-Based Pharmacokinetic (PBPK) Modelling—A Contribution from the ConcePTION Project

Women commonly take medication during lactation. Currently, there is little information about the exposure-related safety of maternal medicines for breastfed infants. The aim was to explore the performance of a generic physiologically-based pharmacokinetic (PBPK) model to predict concentrations in h...

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Detalles Bibliográficos
Autores principales: Nauwelaerts, Nina, Macente, Julia, Deferm, Neel, Bonan, Rodolfo Hernandes, Huang, Miao-Chan, Van Neste, Martje, Bibi, David, Badee, Justine, Martins, Frederico S., Smits, Anne, Allegaert, Karel, Bouillon, Thomas, Annaert, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223637/
https://www.ncbi.nlm.nih.gov/pubmed/37242712
http://dx.doi.org/10.3390/pharmaceutics15051469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223637/
https://www.ncbi.nlm.nih.gov/pubmed/37242712
http://dx.doi.org/10.3390/pharmaceutics15051469

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