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Liposome Formulations for the Strategic Delivery of PARP1 Inhibitors: Development and Optimization

The development of a lipid nano-delivery system was attempted for three specific poly (ADP-ribose) polymerase 1 (PARP1) inhibitors: Veliparib, Rucaparib, and Niraparib. Simple lipid and dual lipid formulations with 1,2-dipalmitoyl-sn-glycero-3-phospho-rac-(1′-glycerol) sodium salt (DPPG) and 1,2-dip...

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Detalles Bibliográficos
Autores principales: Conceição, Carlota J. F., Moe, Elin, Ribeiro, Paulo A., Raposo, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223686/
https://www.ncbi.nlm.nih.gov/pubmed/37242030
http://dx.doi.org/10.3390/nano13101613