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Validation of Freshly Isolated Rat Renal Cells as a Tool for Preclinical Assessment of Radiolabeled Receptor-Specific Peptide Uptake in the Kidney

The synthetic analogs of regulatory peptides radiolabeled with adequate radionuclides are perspective tools in nuclear medicine. However, undesirable uptake and retention in the kidney limit their application. Specific in vitro methods are used to evaluate undesirable renal accumulation. Therefore,...

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Detalles Bibliográficos
Autores principales: Barta, Pavel, Nachtigal, Petr, Maixnerova, Jana, Zemankova, Lenka, Trejtnar, Frantisek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223737/
https://www.ncbi.nlm.nih.gov/pubmed/37242479
http://dx.doi.org/10.3390/ph16050696