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The Potent Antitumor Activity of Smp43 against Non-Small-Cell Lung Cancer A549 Cells via Inducing Membranolysis and Mitochondrial Dysfunction

Research has been conducted to investigate the potential application of scorpion venom-derived peptides in cancer therapy. Smp43, a cationic antimicrobial peptide from Scorpio maurus palmatus venom, has been found to exhibit suppressive activity against the proliferation of multiple cancer cell line...

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Detalles Bibliográficos
Autores principales: Deng, Ze, Gao, Yahua, Nguyen, Tienthanh, Chai, Jinwei, Wu, Jiena, Li, Jiali, Abdel-Rahman, Mohamed A., Xu, Xueqing, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223799/
https://www.ncbi.nlm.nih.gov/pubmed/37235381
http://dx.doi.org/10.3390/toxins15050347