Identification of the Hepatic Metabolites of Flumazenil and their Kinetic Application in Neuroimaging

Studies of the neurobiological causes of anxiety disorders have suggested that the γ-aminobutyric acid (GABA) system increases synaptic concentrations and enhances the affinity of GABA(A) (type A) receptors for benzodiazepine ligands. Flumazenil antagonizes the benzodiazepine-binding site of the GAB...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Hsi, Chiu, Chuang-Hsin, Farn, Shiou-Shiow, Cheng, Kai-Hung, Huang, Yuan-Ruei, Lee, Shih-Ying, Fang, Yao-Ching, Lin, Yu-Hua, Chang, Kang-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223822/
https://www.ncbi.nlm.nih.gov/pubmed/37242547
http://dx.doi.org/10.3390/ph16050764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223822/
https://www.ncbi.nlm.nih.gov/pubmed/37242547
http://dx.doi.org/10.3390/ph16050764

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