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Identification of the Hepatic Metabolites of Flumazenil and their Kinetic Application in Neuroimaging

Studies of the neurobiological causes of anxiety disorders have suggested that the γ-aminobutyric acid (GABA) system increases synaptic concentrations and enhances the affinity of GABA(A) (type A) receptors for benzodiazepine ligands. Flumazenil antagonizes the benzodiazepine-binding site of the GAB...

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Detalles Bibliográficos
Autores principales:	Chen, Wei-Hsi, Chiu, Chuang-Hsin, Farn, Shiou-Shiow, Cheng, Kai-Hung, Huang, Yuan-Ruei, Lee, Shih-Ying, Fang, Yao-Ching, Lin, Yu-Hua, Chang, Kang-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223822/ https://www.ncbi.nlm.nih.gov/pubmed/37242547 http://dx.doi.org/10.3390/ph16050764

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