Cargando…

Synthesis, Pharmacological Evaluation, and Molecular Modeling of Lappaconitine–1,5-Benzodiazepine Hybrids

Diterpenoid alkaloids, originating from the amination of natural tetracyclic diterpenes, have long interested scientists due to their medicinal uses and infamous toxicity which has limited the clinical application of the native compound. Alkaloid lappaconitine extracted from various Aconitum and Del...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheremnykh, Kirill P., Bryzgalov, Arkadiy O., Baev, Dmitry S., Borisov, Sergey A., Sotnikova, Yulia S., Savelyev, Victor A., Tolstikova, Tatyana G., Sagdullaev, Shamansur S., Shults, Elvira E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223824/
https://www.ncbi.nlm.nih.gov/pubmed/37241973
http://dx.doi.org/10.3390/molecules28104234