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Bulk Flow Optimisation of Amorphous Solid Dispersion Excipient Powders through Surface Modification
Particulate amorphous solid dispersions (ASDs) have been recognised for their potential to enhance the performance of various solid dose forms, especially oral bioavailability and macromolecule stability. However, the inherent nature of spray-dried ASDs leads to their surface cohesion/adhesion, incl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223830/ https://www.ncbi.nlm.nih.gov/pubmed/37242689 http://dx.doi.org/10.3390/pharmaceutics15051447 |