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Impacts of PEGylation and Glycosylation on the Biological Properties of Host Defense Peptide IDR1018

The multifunctional properties of host defense peptides (HDPs) make them promising drug candidates to tackle bacterial infections and tissue inflammation. However, these peptides tend to aggregate and can harm host cells at high doses, potentially limiting their clinical use and applications. In thi...

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Detalles Bibliográficos
Autores principales: Etayash, Hashem, Yip, Fione, Hancock, Robert E. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223877/
https://www.ncbi.nlm.nih.gov/pubmed/37242633
http://dx.doi.org/10.3390/pharmaceutics15051391