Design, Synthesis, and Anti-Proliferative Action of Purine/Pteridine-Based Derivatives as Dual Inhibitors of EGFR and BRAF(V600E)

The investigation of novel EGFR and BRAF(V600E) dual inhibitors is intended to serve as targeted cancer treatment. Two sets of purine/pteridine-based derivatives were designed and synthesized as EGFR/BRAF(V600E) dual inhibitors. The majority of the compounds exhibited promising antiproliferative act...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Kalyoubi, Samar A., Gomaa, Hesham A. M., Abdelhafez, Elshimaa M. N., Ramadan, Mohamed, Agili, Fatimah, Youssif, Bahaa G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223936/
https://www.ncbi.nlm.nih.gov/pubmed/37242499
http://dx.doi.org/10.3390/ph16050716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223936/
https://www.ncbi.nlm.nih.gov/pubmed/37242499
http://dx.doi.org/10.3390/ph16050716

Ejemplares similares