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Effect of Inhibiting Butyrylcholinesterase Activity Using Fractionated Coffee Extracts Digested In Vitro in Gastrointestinal Tract: Docking Simulation and Calorimetric and Studies

Butyrylcholinesterase (BChE) is a major enzyme from the alpha-glycoprotein family that catalyzes the hydrolysis of neurotransmitter acetylcholine (ACh), lowering the concentration of ACh in the nervous system, which could cause aggravation of Alzheimer’s disease (AD). In select pathological conditio...

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Detalles Bibliográficos
Autores principales: Grzelczyk, Joanna, Szwajgier, Dominik, Baranowska-Wójcik, Ewa, Pérez-Sánchez, Horacio, Carmena-Bargueño, Miguel, Sosnowska, Bożena, Budryn, Grażyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224059/
https://www.ncbi.nlm.nih.gov/pubmed/37242249
http://dx.doi.org/10.3390/nu15102366