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Effect of Inhibiting Butyrylcholinesterase Activity Using Fractionated Coffee Extracts Digested In Vitro in Gastrointestinal Tract: Docking Simulation and Calorimetric and Studies
Butyrylcholinesterase (BChE) is a major enzyme from the alpha-glycoprotein family that catalyzes the hydrolysis of neurotransmitter acetylcholine (ACh), lowering the concentration of ACh in the nervous system, which could cause aggravation of Alzheimer’s disease (AD). In select pathological conditio...
Autores principales: | Grzelczyk, Joanna, Szwajgier, Dominik, Baranowska-Wójcik, Ewa, Pérez-Sánchez, Horacio, Carmena-Bargueño, Miguel, Sosnowska, Bożena, Budryn, Grażyna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224059/ https://www.ncbi.nlm.nih.gov/pubmed/37242249 http://dx.doi.org/10.3390/nu15102366 |
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