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Engineering Adenoviral Vectors with Improved GBM Selectivity

Glioblastoma (GBM) is the most common and aggressive adult brain cancer with an average survival rate of around 15 months in patients receiving standard treatment. Oncolytic adenovirus expressing therapeutic transgenes represent a promising alternative treatment for GBM. Of the many human adenoviral...

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Detalles Bibliográficos
Autores principales: Bates, Emily A., Lovatt, Charlotte, Plein, Alice R., Davies, James A., Siebzehnrubl, Florian A., Parker, Alan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224093/
https://www.ncbi.nlm.nih.gov/pubmed/37243172
http://dx.doi.org/10.3390/v15051086