PROTACs: Emerging Targeted Protein Degradation Approaches for Advanced Druggable Strategies

A potential therapeutic strategy to treat conditions brought on by the aberrant production of a disease-causing protein is emerging for targeted protein breakdown using the PROTACs technology. Few medications now in use are tiny, component-based and utilize occupancy-driven pharmacology (MOA), which...

Descripción completa

Detalles Bibliográficos
Autores principales: Sincere, Nuwayo Ishimwe, Anand, Krishnan, Ashique, Sumel, Yang, Jing, You, Chongge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224132/
https://www.ncbi.nlm.nih.gov/pubmed/37241755
http://dx.doi.org/10.3390/molecules28104014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224132/
https://www.ncbi.nlm.nih.gov/pubmed/37241755
http://dx.doi.org/10.3390/molecules28104014

Ejemplares similares