Exploration of Novel Urolithin C Derivatives as Non-Competitive Inhibitors of Liver Pyruvate Kinase

The inhibition of liver pyruvate kinase could be beneficial to halt or reverse non-alcoholic fatty liver disease (NAFLD), a progressive accumulation of fat in the liver that can lead eventually to cirrhosis. Recently, urolithin C has been reported as a new scaffold for the development of allosteric...

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Detalles Bibliográficos
Autores principales: Battisti, Umberto Maria, Monjas, Leticia, Akladios, Fady, Matic, Josipa, Andresen, Eric, Nagel, Carolin H., Hagkvist, Malin, Håversen, Liliana, Kim, Woonghee, Uhlen, Mathias, Borén, Jan, Mardinoğlu, Adil, Grøtli, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224133/
https://www.ncbi.nlm.nih.gov/pubmed/37242451
http://dx.doi.org/10.3390/ph16050668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224133/
https://www.ncbi.nlm.nih.gov/pubmed/37242451
http://dx.doi.org/10.3390/ph16050668

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