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l-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway

BACKGROUND: Knee osteoarthritis (KOA) is a disability-associated condition that is rapidly growing with the increase in obesity rates worldwide. There is a pressing need for precise management and timely intervention in the development of KOA. l-carnitine has been frequently recommended as a supplem...

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Detalles Bibliográficos
Autores principales: Liao, Taiyang, Mei, Wei, Zhang, Li, Ding, Liang, Yang, Nan, Wang, Peimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224224/
https://www.ncbi.nlm.nih.gov/pubmed/37237380
http://dx.doi.org/10.1186/s13018-023-03872-9