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Mouse embryonic stem cell-derived blood–brain barrier model: applicability to studying antibody triggered receptor mediated transcytosis

Blood brain barrier (BBB) models in vitro are an important tool to aid in the pre-clinical evaluation and selection of BBB-crossing therapeutics. Stem cell derived BBB models have recently demonstrated a substantial advantage over primary and immortalized brain endothelial cells (BECs) for BBB model...

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Detalles Bibliográficos
Autores principales: Jezierski, Anna, Huang, Jez, Haqqani, Arsalan S., Haukenfrers, Julie, Liu, Ziying, Baumann, Ewa, Sodja, Caroline, Charlebois, Claudie, Delaney, Christie E., Star, Alexandra T., Liu, Qing, Stanimirovic, Danica B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224255/
https://www.ncbi.nlm.nih.gov/pubmed/37237379
http://dx.doi.org/10.1186/s12987-023-00437-0