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Application of Sucrose Acetate Isobutyrate in Development of Co-Amorphous Formulations of Tacrolimus for Bioavailability Enhancement

The focus of the present work was to develop co-amorphous dispersion (CAD) formulations of tacrolimus (TAC) using sucrose acetate isobutyrate as a carrier, evaluate by in vitro and in vivo methods and compare its performance with hydroxypropyl methylcellulose (HPMC) based amorphous solid dispersion...

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Detalles Bibliográficos
Autores principales: Mohamed, Eman M., Dharani, Sathish, Nutan, Mohammad T. H., Cook, Phillip, Arunagiri, Rajendran, Khan, Mansoor A., Rahman, Ziyaur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224275/
https://www.ncbi.nlm.nih.gov/pubmed/37242683
http://dx.doi.org/10.3390/pharmaceutics15051442