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Hydroxypropyl-β-Cyclodextrin Depletes Membrane Cholesterol and Inhibits SARS-CoV-2 Entry into HEK293T-ACE(hi) Cells

Vaccination has drastically decreased mortality due to coronavirus disease 19 (COVID-19), but not the rate of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Alternative strategies such as inhibition of virus entry by interference with angiotensin-I-converting enzyme 2 (ACE2) recept...

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Detalles Bibliográficos
Autores principales: Alboni, Silvia, Secco, Valentina, Papotti, Bianca, Vilella, Antonietta, Adorni, Maria Pia, Zimetti, Francesca, Schaeffer, Laurent, Tascedda, Fabio, Zoli, Michele, Leblanc, Pascal, Villa, Erica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224288/
https://www.ncbi.nlm.nih.gov/pubmed/37242317
http://dx.doi.org/10.3390/pathogens12050647