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Ursodeoxycholic acid induces sarcopenia associated with decreased protein synthesis and autophagic flux

BACKGROUND: Skeletal muscle generates force and movements and maintains posture. Under pathological conditions, muscle fibers suffer an imbalance in protein synthesis/degradation. This event causes muscle mass loss and decreased strength and muscle function, a syndrome known as sarcopenia. Recently,...

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Detalles Bibliográficos
Autores principales: Orozco-Aguilar, Josué, Tacchi, Franco, Aguirre, Francisco, Valero-Breton, Mayalen, Castro-Sepulveda, Mauricio, Simon, Felipe, Cabello-Verrugio, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224307/
https://www.ncbi.nlm.nih.gov/pubmed/37237400
http://dx.doi.org/10.1186/s40659-023-00431-8