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Ursodeoxycholic acid induces sarcopenia associated with decreased protein synthesis and autophagic flux
BACKGROUND: Skeletal muscle generates force and movements and maintains posture. Under pathological conditions, muscle fibers suffer an imbalance in protein synthesis/degradation. This event causes muscle mass loss and decreased strength and muscle function, a syndrome known as sarcopenia. Recently,...
Autores principales: | Orozco-Aguilar, Josué, Tacchi, Franco, Aguirre, Francisco, Valero-Breton, Mayalen, Castro-Sepulveda, Mauricio, Simon, Felipe, Cabello-Verrugio, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224307/ https://www.ncbi.nlm.nih.gov/pubmed/37237400 http://dx.doi.org/10.1186/s40659-023-00431-8 |
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