Protein Fitness Prediction Is Impacted by the Interplay of Language Models, Ensemble Learning, and Sampling Methods

Advances in machine learning (ML) and the availability of protein sequences via high-throughput sequencing techniques have transformed the ability to design novel diagnostic and therapeutic proteins. ML allows protein engineers to capture complex trends hidden within protein sequences that would oth...

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Detalles Bibliográficos
Autores principales: Mardikoraem, Mehrsa, Woldring, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224321/
https://www.ncbi.nlm.nih.gov/pubmed/37242577
http://dx.doi.org/10.3390/pharmaceutics15051337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224321/
https://www.ncbi.nlm.nih.gov/pubmed/37242577
http://dx.doi.org/10.3390/pharmaceutics15051337

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