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Trisubstituted 1,3,5-Triazines as Histamine H(4) Receptor Antagonists with Promising Activity In Vivo

Pain is a very unpleasant experience that makes life extremely uncomfortable. The histamine H(4) receptor (H(4)R) is a promising target for the treatment of inflammatory and immune diseases, as well as pain. H(4)R ligands have demonstrated analgesic effects in a variety of pain models, including inf...

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Detalles Bibliográficos
Autores principales: Olejarz-Maciej, Agnieszka, Mogilski, Szczepan, Karcz, Tadeusz, Werner, Tobias, Kamińska, Katarzyna, Kupczyk, Jarosław, Honkisz-Orzechowska, Ewelina, Latacz, Gniewomir, Stark, Holger, Kieć-Kononowicz, Katarzyna, Łażewska, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224356/
https://www.ncbi.nlm.nih.gov/pubmed/37241939
http://dx.doi.org/10.3390/molecules28104199