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A Novel Flow Cytometry-Based Assay for the Identification of HCN4 CNBD Ligands

Hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels are promising therapeutic targets because of their association with the genesis of several diseases. The identification of selective compounds that alter cAMP-induced ion channel modulation by binding to the cyclic nucleotide-bin...

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Detalles Bibliográficos
Autores principales: Wojciechowski, Magdalena N., Schreiber, Sebastian, Jose, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224427/
https://www.ncbi.nlm.nih.gov/pubmed/37242492
http://dx.doi.org/10.3390/ph16050710