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A Novel Flow Cytometry-Based Assay for the Identification of HCN4 CNBD Ligands
Hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels are promising therapeutic targets because of their association with the genesis of several diseases. The identification of selective compounds that alter cAMP-induced ion channel modulation by binding to the cyclic nucleotide-bin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224427/ https://www.ncbi.nlm.nih.gov/pubmed/37242492 http://dx.doi.org/10.3390/ph16050710 |