Structural Manipulations of Marine Natural Products Inspire a New Library of 3-Amino-1,2,4-Triazine PDK Inhibitors Endowed with Antitumor Activity in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the main aggressive types of cancer, characterized by late prognosis and drug resistance. Among the main factors sustaining PDAC progression, the alteration of cell metabolism has emerged to have a key role in PDAC cell proliferation, invasion, and r...

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Detalles Bibliográficos
Autores principales: Carbone, Daniela, De Franco, Michele, Pecoraro, Camilla, Bassani, Davide, Pavan, Matteo, Cascioferro, Stella, Parrino, Barbara, Cirrincione, Girolamo, Dall’Acqua, Stefano, Sut, Stefania, Moro, Stefano, Gandin, Valentina, Diana, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224441/
https://www.ncbi.nlm.nih.gov/pubmed/37233482
http://dx.doi.org/10.3390/md21050288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224441/
https://www.ncbi.nlm.nih.gov/pubmed/37233482
http://dx.doi.org/10.3390/md21050288

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