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Construction of a Triple-Gene Deletion Mutant of Orf Virus and Evaluation of Its Safety, Immunogenicity and Protective Efficacy

Contagious ecthyma is a zoonotic disease caused by the orf virus (ORFV). Since there is no specific therapeutic drug available, vaccine immunization is the main tool to prevent and control the disease. Previously, we have reported the construction of a double-gene deletion mutant of ORFV (rGS14ΔCBPΔ...

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Detalles Bibliográficos
Autores principales: Shen, Zhanning, Liu, Bo, Zhu, Zhen, Du, Jige, Zhou, Zhiyu, Pan, Chenfan, Chen, Yong, Yin, Chunsheng, Luo, Yufeng, Li, Huanrong, Chen, Xiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224447/
https://www.ncbi.nlm.nih.gov/pubmed/37243014
http://dx.doi.org/10.3390/vaccines11050909